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Global Journal of Parasitology

Global Journal of Parasitology - Volume 1

Parasites and Cancer - A Molecular Insight

Published on: 29 October 2015

Pages: 1-7

Shanju Sankar

Division of Biochemistry, Malabar Cancer Centre, Thalassery-670103, Kerala, India.

Abstract:

Cancer due to parasitic infection is one of the important causes of cancer. Parasites have an oncogenic potential of causing tumor formation in humans. Trematode parasite species such as Schistosoma haematobium and liver flukes such as Opisthorchis viverrini, Clonorchis sinensis are the major cause of bladder cancer. p53 is most widely used genetic marker in the bladder cancer. Micro RNA’s that are differentially expressed in cancer cells, compared to that of normal cells could be used as marker for functional analysis of up regulation and down regulation of genes. Further research on functional characterization of Micro RNA’s could eventually lead to the development of Micro RNA based therapeutics.

Keywords: Parasites, Cancer, Micro RNA’s, Therapeutics.

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